research / skill

Scientific Agent Skills

A library of skills that give an AI coding agent documented workflows for science packages, databases, and research tasks.

At a glance

Purpose
A library of skills that give an AI coding agent documented workflows for science packages, databases, and research tasks.
Runs in
Local agent with shell
Operating systems
macOS, Linux, Windows
Needs
Runtime: uv; Needs internet: Yes; Needs accounts or API keys beyond your agent: Not stated
Files and data
Reads files: Yes; Writes files: Yes; Sends data to other services: Yes
Tool type
Skill
Delivery
From GitHub
Version
Latest on the main branch
Access
Code on GitHub
Compatibility
According to the README, the collection works with Cursor, Claude Code, Claude Cowork, Codex, Gemini CLI, Google Antigravity, GitHub Copilot, VS Code, Kiro, OpenClaw, NemoClaw, Pi, Hermes, and other hosts that support the open Agent Skills standard.
External costs
The repository is MIT-licensed and states no price for itself. According to the README, individual skills connect to named external databases and services, and its Database Lookup skill documents 80 databases with public, registered, or licensed access; the README does not say which of them need an account or a licence. Each skill lists its own credential and network requirements. The README also says commercial support is available, without prices.
Permissions
The skills act through your coding agent with the access you give it. According to the README, skills can run Python code through packages installed with uv and make network requests to the databases and APIs they document. The README warns that skills can instruct your agent to run arbitrary code, install packages, make network requests and modify files on your system, and says to review what you install. Its steps for installing uv on macOS and Linux pipe a downloaded install script into sh, and its install routes place skill files in your agent's skills folders, for example ~/.agents/skills/.
Usage terms
MIT License, as stated in the repository. See its LICENSE.md file for the exact terms.

Code on GitHub

K-Dense-AI/scientific-agent-skills

MIT

Python48,570 stars4,363 forksLast pushed 12 Oct 2026 UTC

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 250,000+ scientists worldwide. 177 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigrav

Topics: agent-skills ai-scientist bioinformatics chemoinformatics claude claude-skills claudecode clinical-research

Public GitHub data fetched · 0 days old

Skill folders in this repository (177)

Folders that contain a SKILL.md file, from GitHub's file list on .

And 77 more in the repository.

View on GitHub ↗

What it does

Scientific Agent Skills is a collection of skills for AI coding agents, created by K-Dense. According to the README, it covers biology, chemistry, medicine, physics, engineering, Earth science, data analysis, and scientific communication, with 177 skills, each documenting the conventions and validation checks for one package, data source, or workflow.

The README groups the skills by area: bioinformatics and genomics, cheminformatics and drug discovery, proteomics, clinical research, healthcare AI and biosignal research, microscopy and medical imaging, neuroscience, machine learning, materials science, physics and astronomy, engineering and simulation, data analysis and visualization, geospatial science, laboratory automation, scientific communication, multi-omics, protein engineering, and regulatory or standards documentation. A dedicated Database Lookup skill documents access to 80 named scientific and financial databases.

According to the README, the agent can already use any Python package or API on its own; these skills add documentation and examples for the ones listed. The README also says it runs weekly LLM-based security scans on the skills in the repository and recommends reading each SKILL.md and scanning a skill yourself before installing it, since community contributions are not all reviewed to the same depth.

Who it is for

Scientists, researchers, and engineers who want an AI coding agent to follow documented workflows for specific scientific packages, databases, or research tasks.

Example tasks

Query a chemical database for candidate compounds and analyze structure-activity relationships.
Load single-cell RNA-seq data and run quality control and cell-type analysis.
Draft a costed experimental protocol from a planned experiment.
Search the literature and generate evidence-bound hypotheses for a research question.
Build a publication-quality figure, slide, or poster from a dataset.

Getting started

The README's main route is "npx skills add K-Dense-AI/scientific-agent-skills" on a supported host. It also documents installing with the GitHub CLI ("gh skill install K-Dense-AI/scientific-agent-skills") and, for Cursor or Codex, loading the repository as an Agent Plugins package. The README has the exact commands.

Limitations

Needs Python 3.13 or later for the repository's own tooling, plus uv as the package manager for skill dependencies; individual skills may support a broader Python range. Needs a host that supports the Agent Skills standard, such as Cursor, Claude Code, Codex, Gemini CLI, or Google Antigravity, per the README. The README lists macOS, Linux, or Windows with WSL2 as the supported systems. It describes its healthcare AI and biosignal skills as research and retrospective validation, not patient-specific diagnosis, treatment, alarms or deployment decisions, and its regulatory and standards skills as drafts prepared for qualified review, not a certification, accreditation or method-release decision. Each skill lists its own package, system-tool, credential, and network requirements separately, and installing the skill files does not install their dependencies. The repository can change at any time; check its README before you install.

Data practices

The README does not give one data-handling statement for all 177 skills. It says each skill's SKILL.md documents what packages it uses and what external service it connects to, so what is sent where depends on which skill you use and your own coding agent and credentials.

Community experience

Not rated yet

Sign in to share your experience.

Comments 0

No comments yet.

Sign in to comment

Report a listing concern